Frequently Asked Questions (FAQs)

How long does the ACTEMRA Co-pay Card Program last?

You may receive up to $15,000 in assistance per 12-month period. Program benefits reset every 12 months from date of enrollment as long as you remain eligible.

If I switch from ACTEMRA intravenous (IV) to ACTEMRA for self-injection (or vice versa), do I have to reapply to the program?

ACTEMRA Intravenous (IV) and ACTEMRA for self-injection are FDA-approved for use in moderate to severe RA patients that have had an inadequate response to a DMARD and patients with polyarticular juvenile idiopathic arthritis (PJIA). If you are this type of patient, and switching from ACTEMRA IV to ACTEMRA for self-injection, you do not need to reapply for the program. Once you qualify and are enrolled in the program, you are eligible to receive $15,000 per 12-month period, subject to submission of documents required for funding of the card with co-pay assistance payments. Note that ACTEMRA for self-injection is not approved for use in patients with systemic juvenile idiopathic arthritis (SJIA) and ACTEMRA IV is not approved for use in giant cell arteritis (GCA) patients. The ACTEMRA Co-Pay Card Program provides drug co-pay assistance for out-of-pocket costs of ACTEMRA only when ACTEMRA IV or ACTEMRA self-injection is prescribed for an approved use.

If I switch from one Genentech medicine to the other, do I have to reapply to the program?

Yes. Each card can be used for either Rituxan or ACTEMRA only. If you switch to a different Genentech medicine , you must reapply to receive assistance for the new medicine.

What if I forgot to apply and have already received treatment?

You must be enrolled in the program before your treatment. However, under certain circumstances, an exception may be possible. Please call (855) RA-COPAY (855-722-6729) for more information.

How many treatments does the program cover?

There is no limit to the number of Rituxan or ACTEMRA treatments the program covers. Treatments will be covered until the $15,000 limit is reached.

Does the program help with the costs of the intravenous (IV) infusion or doctor's visits?

No. The program only helps with the drug co-pay for ACTEMRA. It does not help with other costs, like IV infusions or doctor's visits.

Can the program be used by ACTEMRA patients with giant cell arteritis (GCA)?

Yes. The program is available to all eligible commercially insured ACTEMRA for self-injection patients with giant cell arteritis (GCA).

Can the program be used by ACTEMRA patients with systemic juvenile idiopathic arthritis (SJIA) or polyarticular juvenile idiopathic arthritis (PJIA) who are under 18?

Yes. The program is available to all eligible commercially insured patients taking ACTEMRA for an approved indication. The patient's guardian or legally authorized person who is 18 years or older would need to apply for the co-pay assistance on behalf of the patient under 18.

What if I forget to bring the card to the appointment?

You can call (855) RA-COPAY (855-722-6729) from your doctor's office. The help desk hours are from 6 a.m.–5 p.m. PT, Monday through Friday, except major holidays. We will give the account number over the phone.

May I use the ACTEMRA Co-pay Card Program at an outside infusion center?

Yes. You may use the program anywhere you get your ACTEMRA treatments as long as your infusion center accepts the card.

Will I be asked for other information once I am enrolled in the program?

Yes. You will be asked to send copies of your detailed Explanation of Benefits (EOB) statements after each infusion or injection. This information is required to fund the card.

Can I use the Genentech® Access to Care Foundation (GATCF) and the ACTEMRA Co-pay Card Program at the same time?

No. Patients who are getting help with their drug co-pay for ACTEMRA from GATCF or other patient assistance programs cannot use the ACTEMRA Co-pay Card Program. Call (866) 681-3261 or visit Genentech-Access.com/Rheumatology to learn more about GATCF and other patient assistance programs from Genentech Rheumatology Access Solutions.

Can I get a refund from a health plan for the co-pay paid by the card?

No. You cannot receive a refund from a health plan or anyone else for the amount paid by the card.

How do I find out how much money is left on the card?

You can log in to your account to learn your card balance and expiration dates. You can also call (855) RA-COPAY (855-722-6729) from 6 a.m.–5 p.m. PT, Monday through Friday, except major holidays.


If you have any additional questions, please call (855) RA-COPAY (855-722-6729) from 6 a.m.–5 p.m. PT, Monday through Friday, except major holidays.

Indication and Important Safety Information

ACTEMRA is a prescription medicine used to treat:

  • Adults with moderately to severely active rheumatoid arthritis (RA) after at least one other medicine called a disease modifying antirheumatic drug (DMARD) has been used and did not work well
  • Adults with giant cell arteritis (GCA)
  • Patients with active polyarticular juvenile idiopathic arthritis (PJIA) 2 years of age and older
  • Patients with active systemic juvenile idiopathic arthritis (SJIA) 2 years of age and older

ACTEMRA is not approved for subcutaneous use in people with SJIA.

It is not known if ACTEMRA is safe and effective in children with PJIA or SJIA under 2 years of age or in children with conditions other than PJIA or SJIA.

ACTEMRA can cause serious side effects

Serious Infections

ACTEMRA changes the way your immune system works. This can make you more likely to get infections or make any current infection worse. Some people have died from these infections. Your healthcare provider should test you for TB before starting and during treatment with ACTEMRA.

Do not take ACTEMRA if you are allergic to tocilizumab, or any of the ingredients in ACTEMRA.

ACTEMRA can cause other serious side effects. These include:

Tears (perforation) of the Stomach or Intestines
If you have diverticulitis (inflammation in parts of the large intestine), talk to your healthcare provider before taking ACTEMRA. Some people taking ACTEMRA may develop a hole in the wall of their stomach or intestines (also known as a perforation).

Changes in Blood Test Results
Your healthcare provider should do blood tests before you start receiving ACTEMRA. You should not receive ACTEMRA if your neutrophil and platelet counts are too low or your liver function test levels are too high. These may cause your healthcare provider to stop your ACTEMRA treatment for a time or change your dose.

Cancer
ACTEMRA may increase your risk of certain cancers by changing the way your immune system works.

Hepatitis B Infection
If you have or are a carrier of the hepatitis B virus (a virus that affects the liver), the virus may become active while you use ACTEMRA. Your healthcare provider may do blood tests before you start treatment with ACTEMRA and while you are using ACTEMRA.

Serious Allergic Reactions
Serious allergic reactions, including death, can happen with ACTEMRA. These reactions can happen with any infusion or injection of ACTEMRA, even if they did not occur with an earlier infusion or injection.

Nervous System Problems
While rare, Multiple Sclerosis has been diagnosed in people who take ACTEMRA.

The most common side effects of ACTEMRA include:

  • upper respiratory tract infections (common cold, sinus infections)
  • headache
  • increased blood pressure (hypertension)
  • injection site reactions

ACTEMRA & Pregnancy

Tell your healthcare provider if you are planning to become pregnant, are pregnant, plan to breast-feed, or are breast-feeding. If you are pregnant and taking ACTEMRA, join the pregnancy registry. To learn more, call 1-877-311-8972 or talk to your healthcare provider to register.

Tell your healthcare provider if you have any side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Genentech at 1-888-835-2555.

Please see full Prescribing Information and the Medication Guide, including Serious Side Effects, for more Important Safety Information.